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ChemistryMediumNumerical2016 · 09 Apr Online

Q60.Consider the following sequence for aspartic acid: The pH (Isoelectric point) of aspartic acid is: (1) 3.65 (2) 2.77 (3) 5.74 (4) 1.88

What This Question Tests

The question requires calculating the isoelectric point (pI) for aspartic acid, an acidic amino acid. For acidic amino acids, pI is the average of the pKa values of the two carboxyl groups (alpha-COOH and side-chain COOH).

Concepts Tested

Aspartic acid structurepKa values of amino acid functional groupsCalculation of isoelectric point for acidic amino acids

Formulas Used

pI = (pKa₁ + pKa₂) / 2

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